| Autor: |
Ningyu Du, Changqing Guo, Yi Zhang, Juan Lu, Ruili Zhao, Jing Xu, Wei Zhang, Jingrong Liang |
| Předmět: |
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| Zdroj: |
International Journal of Clinical Acupuncture; Apr-Jun2018, Vol. 27 Issue 2, p112-118, 7p |
| Abstrakt: |
Objective: To observe the medial vastus muscular trigger point energy metabolism (adenine nucleotide, lactic acid) changes due to acupotomy intervention and the biological mechanism of treating myofascial pain syndrome with acupotomy using a rat model with myofascial pain syndrome. Methods: The trigger point model rats were established by the method of crush plus eccentric exercise. The pathological variation of trigger points of rats was observed by electrophysiology. The expression of adenine nucleotide and lactic acid on trigger points was verified through high performance liquid chromatography (HPLC) and the colorimetric method. Differences among groups were then analyzed. Results: At the end of 8th week of modeling, in the model group, the levels of adenine nucleotide declined significantly (P < 0.05), and the levels of lactic acid increased significantly (P < 0.05). After three rounds of acupotomy treatment, the levels of adenine nucleotide in the acupotomy therapy group significantly increased, and the levels of lactic acid in the acupotomy therapy group significantly declined compared with those in the model group (P < 0.01). There were also significant differences of adenine nucleotide and lactic acid between the acupotomy therapy group and the normal group after three rounds of acupotomy treatment (P < 0.05). Conclusions: Through releasing and activating the trigger points, acupotomy may promote the release of adenine nucleotide and inhibit the secretion of lactic acid in the local site, improving the continued contracting condition of muscles and reducing the accumulation of metabolic products. In this way, acupotomy may break the vicious cycle and finally cure the myofascial pain syndrome. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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