| Autor: |
Huising, Mark O., van der Meulen, Talitha, Huang, Jessica L., Pourhosseinzadeh, Mohammad S., Noguchi, Glyn M. |
| Předmět: |
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| Zdroj: |
Physiology; Nov2018, Vol. 33 Issue 6, p403-411, 9p |
| Abstrakt: |
The role of beta and α-cells to glucose control are established, but the physiological role of δ-cells is poorly understood. Delta-cells are ideally positioned within pancreatic islets to modulate insulin and glucagon secretion at their source. We review the evidence for a negative feedback loop between delta and β-cells that determines the blood glucose set point and suggest that local δ-cell-mediated feedback stabilizes glycemic control. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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