| Autor: |
Kammoolkon, Ratanee, Taneepanichskul, Nutta, Siriwong, Wattasit, Pitaknoppakul, Nattaporn, Lohsoonthorn, Vitool |
| Předmět: |
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| Zdroj: |
Journal of the Medical Association of Thailand; Nov2018, Vol. 101 Issue 11, p1529-1536, 8p |
| Abstrakt: |
Background: Outdoor particulate matter [PM] has been associated with cardiovascular [CVD] morbidity and mortality. Epidemiological and experimental studies confirmed an association between outdoor PM and carotid artery intima-media thickness [CIMT], which can potentially lead to progression of CVD. However, evidence on the effects of indoor PM on the CVD system is still limited. Objective: To examine the association of long-term exposure to household indoor PM of less than 10 micrometer [PM10] and increased carotid intima-media thickness [CIMT] of the common carotid artery [CCA]. Materials and Methods: A one-year follow-up study was conducted in 104 households located in the central city of Sakon Nakhon province, Thailand. Clinical testing and a carotid artery ultrasound of participants were undertaken between September 2016 and September 2017. Household PM10 concentrations, temperature, and relative humidity [RH] were measured inside the participants' home during the wet and dry seasons. Results: The average of PM10 concentrations was 24.2±11.2 µg/m3. Mean and maximum CIMT at CCA was different between baseline and follow-up (p-value <0.001). Logistics regression models showed that an increase of 1 µg/m3 average household PM10 concentrations were associated with 6% increased risk of increased maximum CIMT of CCA (AOR 1.06; 95% CI 1.02 to 1.11). Conclusion: Household PM10 concentration is associated with increased CIMT of CCA. This finding suggests that household PM10 may be a risk factor for CVD morbidity and mortality. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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