| Autor: |
Coxon, J. P., Oades, G. M., Colston, K. W., Kirby, R. S. |
| Předmět: |
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| Zdroj: |
Prostate Cancer & Prostatic Diseases; 2004, Vol. 7 Issue 2, p99-104, 6p, 3 Color Photographs, 1 Chart |
| Abstrakt: |
Prostate cancer incidence is rising, and represents a major public health issue. Bone is by far the most common site for metastases in this disease, accounting for considerable morbidity. Until recently, there have been few viable options for the treatment of patients with hormone-refractory metastatic disease. This review examines the pathophysiology underlying the development of bone metastases. It also summarises some of the clinical approaches for the management of this common condition, focusing on recent evidence supporting the use of zoledronic acid, a member of one of the most promising groups of pharmacological agents, the third-generation bisphosphonates.Prostate Cancer and Prostatic Diseases (2004) 7, 99-104. doi:10.1038/sj.pcan.4500705 Published online 2 March 2004 [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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