| Autor: |
Siahpoosh, Amir, Majdinasab, Nastaran, Derakhshannezhad, Negin, Khalili, Hamid Reza, Malayeri, Alireza |
| Předmět: |
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| Zdroj: |
Journal of Contemporary Medical Sciences; Summer2018, Vol. 4 Issue 3, p148-152, 5p |
| Abstrakt: |
Objective Multiple sclerosis (MS) is an inflammatory disease in which the myelin sheaths of the neural cells in the brain and the spinal cord are damaged. This injury affects the ability of parts of the nervous system that are responsible for communication and cause many physical and mental signs and symptoms. The grape seed which is scientifically called Vitis vinifera is the native plant in southern Europe and western Asia and its extract has strong antioxidants, anti-inflammatory and neuron and nervous system protection properties. Therefore, it is considered to control the free radicals and inflammation that contribute to the development and progression of MS. Methods The effect of grape seed extract on the fatigue control in patients was investigated as a double-blinded design. About 66 patients, all treated with interferon, were randomly divided into two groups. The first group received placebo for the first month and the second group had grape seed capsules for 1 month. Fatigue was calculated based on multiple sclerosis quality of life-54 before and after the study. The results were analyzed by t-test to compare the mean in both groups and also the pair t-test was applied to compare the fatigue test score before and after the treatment in the groups. Results The results showed that the use of grape seed capsules significantly altered the physical and mental activity of patients with MS. Conclusion The existing MS drugs reduce the number of relapses, severity of disease and prevent disease progression. They have less effect on symptoms and improving performance and the quality of life along with side effects. Due to the absence of significant side effects of grape seed and its proper effect, it can be used to improve fatigue and physical and mental activity in patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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