| Autor: |
Pandey, Shashi, Singh, Deepti, Chauhan, Prem M. S. |
| Předmět: |
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| Zdroj: |
Chemistry & Biology Interface; Jul/Aug2018, Vol. 8 Issue 4, p234-243, 10p |
| Abstrakt: |
An efficient synthetic protocol for the synthesis of highly substituted 2, 5 dihydropyrrole has been developed. The protocol involves K2CO3 mediated carbanion-yne intramolecular cyclization of Ugi-propargyl adducts to afford the 2, 5 dihydropyrrole derivatives in good to excellent yield. Moreover, the nature of the substituents at the benzaldehyde (R2) of the Ugi-propargyl adduct has a crucial effect on the yield of the cyclized product. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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