The active metabolite of leflunomide, A77 1726, inhibits the production of prostaglandin E2, matrix metalloproteinase 1 and interleukin 6 in human fibroblast-like synoviocytes.

Autor: Burger, D., Begué-Pastor, N., Benavent, S., Gruaz, L., Kaufmann, M.-T., Chicheportiche, R., Dayer, J.-M.
Zdroj: Rheumatology; Jan2003, Vol. 42 Issue 1, p89-96, 8p, 6 Graphs
Databáze: Complementary Index