| Autor: |
Sintsov, M. Yu., Suchkov, D. S., Minlebaev, M. G. |
| Předmět: |
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| Zdroj: |
Neuroscience & Behavioral Physiology; Jun2018, Vol. 48 Issue 5, p551-556, 6p |
| Abstrakt: |
Recording of the intrinsic optical signal (IOS) is widely used or functional studies of the cerebral cortex in vivo. Despite the fact that IOS provides for detection of active areas, regardless of the age of the object, it is widely used in studies of the developing brain. However, in immature brains IOS has low amplitude, which hinders its use and requires other recording and analysis methods. We report here our assessment of the use of the principal components analysis (PCA) method for the automatic detection of IOS at the early stages of development of the rat brain. Recording of IOS in infrared light and use of PCA was found to provide reliable detection of IOS in rats in the first three weeks after birth. Addition of artificial noise to IOS showed that detection using PCA was effective in half of cases despite increases in the noise level to four times baseline. These results provide evidence that the PCA method has potential to be used for detecting IOS at the early stages of development and that the PCA method is very robust for detection of IOS. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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