Primary Epstein-Barr virus infection in immunocompetent patients with acute transverse myelitis and a combination of polyradiculitis and anterior horn syndrome as neurological manifestations.

Autor: Poorthuis, Michiel H. F., Battjes, Suzanne, Dorigo-Zetsma, J. Wendelien, de Kruijk, Jelle R.
Zdroj: BMJ Case Reports; 8/29/2018, Vol. 2018, p1-4, 4p, 1 Black and White Photograph
Abstrakt: Neurological manifestations of a primary Epstein- Barr virus (EBV) infection are rare. We describe a case with acute transverse myelitis and another case with a combination of polyradiculitis and anterior horn syndrome as manifestations of a primary EBV infection. The first case is a 50-year-old immunocompetent male diagnosed with acute transverse myelitis, 2 weeks after he was clinically diagnosed with infectious mononucleosis. The second case is an 18-year-old immunocompetent male diagnosed with a combination of polyradiculitis and anterior horn syndrome while he had infectious mononucleosis. The first patient was treated with methylprednisolone. After 1 year, he was able to stop performing clean intermittent selfcatheterisation. The second patient completely recovered within 6 weeks without treatment. Primary EBV infection should be considered in immunocompetent patients presenting with acute transverse myelitis and a combination of polyradiculitis and anterior horn syndrome. Antiviral treatment and steroids are controversial, and the prognosis of neurological sequelae is largely unknown. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index