Frequency of Chronic Atrophic Gastritis among 11543 patients from a Pathology clinical center between 2012 and 2016.

Autor: Behrooznia, Zahra, Ghaderi, Pouya, Jafarzadeh, Narges, Qolipoor, Ahmad, Zargaran, Bita, Delavari Lotf Abad, Shamim, Poorali, Saba, Shariat Razavi, Ali, Mansoori Majoofardi, Sepideh, Moqaddari, Soudeh, Vaghei, Nastaran, Izanloo, Azra, Sima, Ali Reza, Sima, Hamid Reza, Farzanehfar, Mohammad Reza, Goshayeshi, Ladan, Bary, Ali Reza, Mokhtari, Elham, Ghaffarzadehgan, Kamran
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Zdroj: Iranian Journal of Gastroenterology & Hepatology (GOVARESH); 2017 Supplement, Vol. 22 Issue 3, p29-29, 1/2p
Abstrakt: Introduction: Although the global incidence of gastric cancer has been decreased dramatically in recent decades, north and northwest of Iran have the highest incidence rate of gastric cancer. The intestinal type of gastric cancer usually occurs in gastric tissues with chronic Atrophic gastritis. The epidemiologic data of CAG as an important precursor lesion are rare. In this study, we aimed to determine the frequency of CAG based on pathologic reports of upper gastrointestinal biopsy samples from Pathology clinical center in Mashhad, Iran. Methods: In this cross sectional study, pathologic reports of patients diagnosed with gastropathy in upper GI endoscopy from 2012 to 2016 were reviewed. Totally 11543 patients with available and complete pathologic reports enrolled. The patients with incomplete or unclear pathologic reports were excluded. The frequency of CAG and demographic patient's information were analyzed by SPSS version 19 and Chi-squre test was used. Results: The prevalence of CAG was 5.7% among 11543 subjects. Totally 47.3% patients were male and 52.7% were female. The incidence of CAG was 5% and 6% in women and men, respectively. By Chi-square test, there is significant difference in male and female (p = 0.0001). Independent T.test shows the significant correlation between age and CAG, (P = 0.0001). The age range of patients with atrophy varies from 5 to 90 years. The mean age of patients was 58.65 15.09. By Chi-squre test, there is significant correlation between frequent of CAG and regions of gastric (p = 0.0001). The most frequent region of atrophy was antrum. The prevalence of atrophy was statistically higher in H.pylori non-infected individuals (p = 0.0001). Conclusion: In our study, the prevalence of CAG is not higher than estimated incidence rate in meta-analysis. Like most studies, prevalence of CAG has significant correlation with male gender and older age. About the correlation with H.pylori, we can judge better by serological assessment in further studies. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index