| Autor: |
Mali, Prakash R., Khomane, Navnath B., Sridhar, B., Meshram, H. M., Likhar, Pravin R. |
| Předmět: |
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| Zdroj: |
New Journal of Chemistry; 8/21/2018, Vol. 42 Issue 16, p13819-13827, 9p |
| Abstrakt: |
A new series of spiro pyrrole/pyrrolizine/thiazole compounds have been synthesized using (3+2) dipolar cycloaddition via three-component condensation reactions of ninhydrin and α-amino acids with different dipolarophiles such as maleimide, malic anhydride, 2-benzyl-2-methylcyclopent-4-ene-1,3-dione and isothiocyanates. Another four-component protocol has been developed in which ninhydrin, proline, maleimide and phenacyl bromides are reacted to afford a novel library of pyrrolizine derivatives in good yields without the use of catalyst. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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