| Autor: |
Vlasov, Sergiy V., Kovalenko, Sergiy M., Shynkarenko, Pavlo E., Krolenko, Konstantin Yu., Vlasov, Vitaliy S. |
| Předmět: |
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| Zdroj: |
Heterocyclic Communications; Aug2018, Vol. 24 Issue 4, p237-240, 4p |
| Abstrakt: |
Syntheses of 3-(4-arylthieno[2,3-d]pyrimidin- 2-yl)-2H-chromen-2-ones 5 by the reaction of 2-iminocoumarin- 3-carboxamides 1 with (2-aminothiophen-3-yl)(aryl) methanones 2 and by the alternative Suzuki coupling of 4-chlorothieno[2,3-d]pyrimidin-2-yl-2H-chromen-2-one 7 with arylboronic acids were developed. Compound 5d showed higher antimicrobial activity against Staphylococcus aureus than the reference drug streptomycin. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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