| Autor: |
Tartibian, Bakhtyar, Sirwan Mohammad Amini Khayat, Asgarzadeh, Reza |
| Předmět: |
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| Zdroj: |
Iranian Journal of Allergy, Asthma & Immunology; 2018 Supplement, Vol. 17, p219-220, 2p |
| Abstrakt: |
Objective: The aim of this study was to investigation of transforming growth factor- α gene expression and AST, ALT and lipase serum levels changes in response to 8 weeks resistance training. Material and Methods: Totally 26 healthy non-active men (age: 35-55 years, BMI: 25.52 K/m2) were volunteered in this study and randomly divided into control (n=13) and exercise (n=13) groups. The exercise group performed eight weeks resistance training (30 min/day, 3 days/week) by 65% (1RM) on the first weeks until 85% (1RM) on the end of 8 weeks. Body composition, BP, blood samples and transforming growth factor-a gene expression were measured in basal conditions and 48 hours after the training program. Bio Easy Master Mix Kit and Real-time PCR method used for TGF- α gene expression, ELISA method for analyzed of IL-6, IL-12 and standard laboratory methods used for white blood cell counts. Our data have been analyzed by independent t-test on SPSS software version 23. Results: The result showed that TGF- α gene expression in the exercise group compared to control group showed a significant reduction after 8 weeks exercise training (p<0.001). However, AST, ALT and Lipase serum levels in the exercise group compare with control group after 8 weeks resistance training didn't have significant changes (p 0.05). Conclusion: It seems that resistance training by entering less pressure and less damage on liver membranes causes to reduction of TGF- α gene expression as an inflammatory marker and stabilize lipase secreted that finally it decreases the release of AST and ALT to blood as a liver damage indexes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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