Characteristics and Etiology of Pediatric and Adult Anaphylaxis in 3 Tertiary Hospitals in Iran.

Autor: Nabavi, Mohammad, Arshi, Saba, bemanian, Mohammad Hasan, Molatefi, Rasool, Rekabi, Mahsa, Eslami, Narges, Shokri, Sima, Ahmadian, Javad, Darabi, Kian, Sedighi, Reza, Fallahpour, Morteza
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Zdroj: Iranian Journal of Allergy, Asthma & Immunology; 2018 Supplement, Vol. 17, p118-119, 2p
Abstrakt: Objective: Despite increasing prevalence of anaphylaxis there is little information about its characteristics and the practice of health providers in treating anaphylaxis. To record the overall characteristics, etiology and therapeutic approaches of anaphylaxis in adult and pediatric population Material and Methods: From May 2012 until April 2015 we retrospectively collected data of all patients diagnosed as anaphylaxis in the Allergy and Clinical Immunology department of Rasool-e-Akram, Ali Asghar and Firooz abadi hospital, Iran University of Medical sciences, Tehran, Iran. Demographic and clinical features, as well as its triggers and therapeutic approach in attacks were evaluated. Results: 136 individuals, 64 males (47%), between 6 month and 68 years old (21.01±15.26 year), 72 of them (52.94%) under 18 years old (pediatric) were diagnosed anaphylaxis based on world allergy organization criteria. Skin 86.02% (pediatric 91.66% vs. adult 79.68%), respiratory tract 51.47% (pediatric 43.05% vs. adult 60.93%), cardio vascular 50.73% (pediatric 54.16% vs. adult 46.87%), gastrointestinal 20.58% (pediatric 27.7% vs. adult 12.5%) and neurologic system 5.88% (only in adult) were the most common involved organs. Foods 69 (50.37%) [42 pediatric and 27 adult], drugs 34 (25%) [14 pediatric and 20 adult], idiopathic 16 (11.77%) [3 pediatric and 13 adult], insect sting7 (5.15%) [3pediatric and 4 adult], exercise 6(4.42%) [1 pediatric and 5 adult] whom three of them were exercise induced food dependent (1pediatric and 2 adult), vaccine 3 (2.2%) [Only pediatric] and latex1 (0.73 %) were the most identified causes. Milk, egg and wheat were the most common causative foods in pediatric but egg, sesame and milk were the most causes in adult. Drugs were more common in adult [14pediatric vs. 20 adult] with NSAIDs and antibiotics were the most common causes. Conclusion: Cutaneous, respiratory, cardiovascular and gastrointestinal complains were the most common manifestations and food, drug and idiopathic were the most common causes of anaphylaxis in our case series. Anaphylaxis diagnosis, epinephrine subscription and refer to allergist was not optimum but it was significantly better in severe cases when patient was admitted. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index