Association of obesity, diabetes and hypertension with cognitive impairment in older age.

Autor: Feinkohl, Insa, Lachmann, Gunnar, Brockhaus, Wolf-Rüdiger, Borchers, Friedrich, Piper, Sophie K, Ottens, Thomas H, Nathoe, Hendrik M, Sauer, Anne-Mette, Dieleman, Jan M, Radtke, Finn M, Dijk, Diederik van, Pischon, Tobias, Spies, Claudia
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Zdroj: Clinical Epidemiology; Jul2018, Vol. 10, p853-862, 10p
Abstrakt: Background: Age-related cognitive impairment is rising in prevalence but is not yet fully characterized in terms of its epidemiology. Here, we aimed to elucidate the role of obesity, diabetes and hypertension as candidate risk factors. Methods: Original baseline data from 3 studies (OCTOPUS, DECS, SuDoCo) were obtained for secondary analysis of cross-sectional associations of diabetes, hypertension, blood pressure, obesity (body mass index [BMI] ≥30 kg/m²) and BMI with presence of cognitive impairment in log-binomial regression analyses. Cognitive impairment was defined as scoring more than 2 standard deviations below controls on at least one of 5–11 cognitive tests. Underweight participants (BMI [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index