| Autor: |
Moaiery, Hassan, Akbari, Mohammad Esmail, Nafissi, Nahid, Mahdavi, Seied Rabi, Mirzaei, Hamid Reza, Salati, Azam, Khayamzadeh, Maryam, Shormeij, Zeinab, Shakeri, Jafar, Nabatzadeh, Mojgan, Shahani, Mino, Kiaee, Marzieh Sadat, Noorian, Sajad |
| Předmět: |
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| Zdroj: |
International Journal of Cancer Management; Jul2018, Vol. 11 Issue 7, p1-6, 6p |
| Abstrakt: |
Background: Breast conserving surgery and its following radiotherapy is an accepted therapeutic method for patients with invasive lobular carcinoma (ILC). Objectives:We compared clinical outcomes of women diagnosed with ILC or invasive ductal carcinoma (IDC) treated with intraoperative electron radiotherapy (IOERT) boost dose and external beam radiotherapy (EBRT) as whole breast irradiation (WBI) versus EBRT as WBI. Methods: In this retrospective study including 632 patients, who were referred to cancer research center of Shahid Beheshti University from August 2013 to September 2017 and received IORT, after breast-conserving surgery, we compared prognostic factors and ipsilateral breast recurrence (IBR) and distant recurrence (metastasis); 426 patients received a tumor bed boost with IOERT during lumpectomy, 58 patients were pure invasive lobular carcinoma, and 239 patients were pure invasive ductal carcinoma. The patient followed-up to 49 months. We retrospectively analyzed the factors associated with interfering to effects of IOERT with boost dose in the patient with breast cancer. Results: At 4 years, there were 2 cases ipsilateral breast recurrence in the IDC boost IOERT group and 0 cases ILC boost group and there were 5 cases distance or metastatic breast recurrence in the IDC boost IOERT group, and 0 case ILC boost group. Conclusions: Overall, the rates of local recurrence and distant recurrence (metastasis) in the ILC boost IOERT group were signifi- cantly low and compared to the second group, they were not inferior. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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