| Autor: |
de Lisboa Lopes Costa, Antonio, de Araujo, Ney Soares, dos Santos Pinto Jr., Déclo, de Araújo, Vera Cavalcanti |
| Předmět: |
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| Zdroj: |
Journal of Oral Pathology & Medicine; Nov1999, Vol. 28 Issue 10, p438-441, 4p |
| Abstrakt: |
This study was performed on oral squamous cell carcinomas (OSCC) in order to investigate the relation between the number of interphase silver-stained nucleolar organizer regions (AgNORs) and the immunolabeling of proliferation-associated markers, using antibodies to Ki-67 and proliferating cell nuclear antigen (PCNA). Fifteen consecutive cases of oral squamous cell carcinoma were used and a double staining technique was performed in order to quantify the number of NORs in PCNA-positive and -negative cells as well as in Ki-67-positive and -negative cells. Our results showed a higher mean number of AgNORs in PCNA-and Ki-67-positive cells than in PCNA- and Ki-67-negative cells. We concluded that there is an association between cell proliferation and AgNOR score in OSCC. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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