| Autor: |
Kinoshita, Misaki, Lin, Yuxi, Dai, Itoh, Okumura, Masaki, Markova, Natalia, Ladbury, John E., Sterpone, Fabio, Lee, Young-Ho |
| Předmět: |
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| Zdroj: |
Chemical Communications; 7/21/2018, Vol. 54 Issue 57, p7995-7998, 4p |
| Abstrakt: |
Understanding of amyloid aggregation in terms of thermodynamics and kinetics is still limited. We herein examined the mechanism of β2-microglobulin amyloidogenesis using our unique method of isothermal titration calorimetry-based thermodynamic/kinetic measurements, and revealed the energy landscape of polymorphic amyloidogenesis under biological environment-mimicking conditions including shear forces and crowding effects. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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