Microfluidics-enabled rational design of immunomagnetic nanomaterials and their shape effect on liquid biopsy.

Autor: Hao, Nanjing, Nie, Yuan, Shen, Ting, Zhang, John X. J.
Předmět:
Zdroj: Lab on a Chip; 7/21/2018, Vol. 18 Issue 14, p1997-2002, 6p
Abstrakt: Microfluidics brings unique opportunities for the synthesis of nanomaterials toward efficient liquid biopsy. Herein, we developed the microreactor-enabled flow synthesis of immunomagnetic nanomaterials with controllable shapes (sphere, cube, rod, and belt) by simply tuning the flow rates. The particle shape-dependent screening efficiency of circulating tumor cells was first investigated and compared with commercial ferrofluids, providing new insights into the rational design of a particulate system toward the screening and analysis of circulating tumor biomarkers. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index