Bidirectional association between disturbed sleep and neuropathic pain symptoms: a prospective cohort study in post-total joint replacement participants.

Autor: Stocks, Joanne, Tang, Nicole KY, Walsh, David A, Warner, Sophie C, Harvey, Hollie L, Jenkins, Wendy, Abhishek, Abhishek, Doherty, Michael, Valdes, Ana M
Předmět:
Zdroj: Journal of Pain Research; Jun2018, Vol. 11, p1087-1093, 7p
Abstrakt: Background: Disturbed sleep is strongly correlated with chronic pain. The aim of this study was to examine the association between sleep disturbance and incident joint pain focusing on neuropathic-like pain symptoms. Methods: A total of 423 individuals who had undergone total joint replacement (TJR) for osteoarthritis were assessed at the mean time of 3.6 years post-surgery and again at 5.9 years post-TJR, using the Medical Outcomes Survey sleep subscale, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and painDETECT questionnaire instruments. Cox hazard ratios (HRs) and 95% confidence intervals (CIs) were computed adjusting for age, body mass index, sex, and use of hypnotic and analgesic medication. Results: The presence of neuropathic pain symptoms predicted incidence of disturbed sleep after adjustment for covariates and pain severity (adjusted HR [aHR] 2.01, 95% CI: 1.00–4.10; p [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index