Self-assessment of pubertal development in a puberty cohort.

Autor: Ernst, Andreas, Lauridsen, Lea Lykke B., Brix, Nis, Kjersgaard, Camilla, Olsen, Jørn, Parner, Erik T., Clausen, Niels, Olsen, Lars Henning, Ramlau-Hansen, Cecilia H.
Zdroj: Journal of Pediatric Endocrinology & Metabolism; Jul2018, Vol. 31 Issue 7, p763-772, 10p
Abstrakt: Background: We evaluated the inter-rater agreement between self-assessed Tanner staging and clinical examination and the intra-individual agreement of self-assessed information on various puberty markers in late adolescents from the longitudinal nationwide Puberty Cohort, a sub-cohort of the Danish National Birth Cohort (DNBC). Methods: We invited 715 children from the ongoing Puberty Cohort between June 2016 and January 2017. In total, 366 children (51%) returned an add-on questionnaire identical to the questionnaire used to collect information on puberty markers, including Tanner staging, in the Puberty Cohort. Of these, 197 (54%) also participated in a clinical examination with Tanner staging. We used percentage agreement and weighted kappa statistics to evaluate the inter-rater and intra-individual agreement. Results: Due to late entry, more than 75% of children were Tanner stage 4 or above at clinical examination. In girls, the inter-rater agreement for pubic hair and breast staging was 54% and 52%, respectively, yielding weighted kappas of fair strength. In boys, pubic hair and genital staging agreed in 55% and 33%, respectively, corresponding to weighted kappas of fair to moderate strength. Boys tended to underestimate genitalia staging consistently. The intra-individual agreement on Tanner staging was 75-77% in girls and 69% in boys, whereas the intra-individual agreement on axillary hair and acne was above 92%. Conclusions: Self-assessment of late stages of pubertal development may be misclassified, leading to random errors in studies of puberty timing. However, self-assessment continues to serve as an important time- and costsaving tool in large prospective puberty cohorts. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index