Synthesis and Pharmacological Activity of Tris(2-hydroxyethyl)ammonium 4-Chlorophenylsulfonylacetate.

Autor: Adamovich, S. N., Oborina, E. N., Mirskova, A. N.
Předmět:
Zdroj: Russian Journal of Applied Chemistry; Apr2018, Vol. 91 Issue 4, p701-705, 5p
Abstrakt: Methods for the synthesis of 4-chlorophenylsulfonylacetic acid and its tris(2-hydroxyethyl)ammonium salt (“sulfacetamine”) were studied. The results of in vitro and in vivo experiments showed that sulfacetamine possesses high antithrombotic, antioxidant, hypocholesterolemic, immunostimulating, and protective-adaptive activities. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index