A cocktail of 165Er(iii) and Gd(iii) complexes for quantitative detection of zinc using SPECT and MRI.

Autor: Malikidogo, Kyangwi P., Da Silva, Isidro, Morfin, Jean-François, Lacerda, Sara, Barantin, Laurent, Sauvage, Thierry, Sobilo, Julien, Lerondel, Stéphanie, Tóth, Éva, Bonnet, Célia S.
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Zdroj: Chemical Communications; 7/14/2018, Vol. 54 Issue 55, p7597-7600, 4p
Abstrakt: We propose quantitative assessment of zinc by combining nuclear and MR imaging. We use a cocktail of a Gd3+-complex providing a Zn2+-dependent MRI response and its 165Er3+ analogue allowing for concentration assessment. 165Er is readily obtained in a cyclotron and purified, which is indispensable for successful quantification of metal ions. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index