Pathogenic Germline BRCA1/2 Mutations and Familial Predisposition to Gastric Cancer.

Autor: Ichikawa, Hiroshi, Wakai, Toshifumi, Nagahashi, Masayuki, Shimada, Yoshifumi, Hanyu, Takaaki, Kano, Yosuke, Muneoka, Yusuke, Ishikawa, Takashi, Takizawa, Kazuyasu, Tajima, Yosuke, Sakata, Jun, Kobayashi, Takashi, Kemeyama, Hitoshi, Yabusaki, Hiroshi, Nakagawa, Satoru, Sato, Nobuaki, Kawasaki, Takashi, Homma, Keiichi, Okuda, Shujiro, Lyle, Stephen
Předmět:
Zdroj: JCO Precision Oncology; 2018, Vol. 2, p1-8, 8p
Abstrakt: The article focuses on the BRCA1/2 genetic testing in patients with gastric cancer (GC). Topics discussed include an overview of the BRCA1/2 mutations, the determination of pathogenic germline BRCA1/2 mutations with familial GC component, and the association of BRCA1/2 mutations with GC familial predisposition.
Databáze: Complementary Index