| Autor: |
Altaf, Bilal, Shah, Fazal Hussain, Akhtar, Mumtaz, Wasim, Sana |
| Předmět: |
|
| Zdroj: |
Isra Medical Journal; Mar/Apr2018, Vol. 10 Issue 2, p86-90, 5p |
| Abstrakt: |
OBJECTIVE: To compare the role of topical diltiazem and glyceryltrinitrate in terms of healing in chronic anal fissure. STUDY DESIGN: A Randomized Control Trial PLACE AND DURATION: Department of Surgery, Benazir Bhutto Hospital, Rawalpindi from 1st June 2012 to 30th November 2012. METHODOLOGY: All patients with clinical diagnosis of chronic anal fissure were equally divided in two groups. One group received 0.2% glyceryltrinitrate ointment while other received 2% diltiazem paste topically. Both groups were compared in terms of healing and frequency of headache after 6 weeks of treatment. RESULTS: Among total 140 patients, the 85.7% patients had chronic anal fissure posteriorly while rest of patients had it anteriorly. In glyceryltrinitrate group, the healing rate after 6 weeks was 62.9% while in diltiazem group the rate was 78.6% (p value 0.041). The frequencies of headache were 44.3% and 21.4% in glyceryltrinitrate and diltiazem groups respectively (p value 0.004). CONCLUSION: The diltiazem is superior to the glyceryltrinitrate in terms of healing and side effects when used topically for the management of chronic anal fissure. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
