Pathophysiological and clinical aspects of breathing after stroke.

Autor: Howard, R. S., Rudd, A. G., Wolfe, C. D., Williams, A. J.
Předmět:
Zdroj: Postgraduate Medical Journal; Nov2001, Vol. 77 Issue 913, p700-702, 3p
Abstrakt: Stroke may disrupt breathing either by causing a disturbance of central rhythm generation; interrupting the descending respiratory pathways leading to a reduced respiratory drive, or; causing bulbar weakness leading to aspiration. Neural control of respiration in man depends on a central drive to the respiratory muscles which is modulated by chemical and mechanical inputs. While many of the factors control- ling established respiratory rhythm in mammals are understood, the neural mechanisms of rhythm generation remain obscure. It has proved difficult, in man, to attribute precise respiratory function to localised anatomical substrates because lesions are rarely localised and coexisting pulmonary, cardiovascular, or autonomic influences may complicate the clinical picture.
Databáze: Complementary Index