A Course-Based Undergraduate Research Experience Investigating the Consequences of Nonconserved Mutations in Lactate Dehydrogenase.

Autor: Ayella, Allan, Beck, Moriah R.
Předmět:
Zdroj: Biochemistry & Molecular Biology Education; May/Jun2018, Vol. 46 Issue 3, p285-296, 12p
Abstrakt: There is a growing movement to involve undergraduate students in authentic research experiences. A variety of studies have indicated the strength of this approach in developing scientific aptitude, confidence, critical thinking skills, and increasing the likelihood to become career scientists. Coursebased undergraduate research experiences (CUREs) foster opportunities for students to carry out authentic research at both primarily undergraduate and large research institutions. Here, we describe a novel CURE-based biochemistry laboratory course to explore the consequences of mutagenesis of non-conserved amino acid sites in the structure and function of the lactate dehydrogenase enzyme and demonstrate how collaborations between institutions can facilitate real research experiences at any type of institution. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index