| Abstrakt: |
In the present study a total of 48 rats were randomly divided into eight equal groups. The rats of group-I were kept as control. The cypermethrin was given @ 25 mg/kg body weight (corn oil) orally in the rats of group-II, III, IV and group-VIII. The rats of group-III, V, VI and VIII were administered with sodium fluoride @ 8 mg/kg body weight (distilled water) orally. Vitamin E was given @ 100 mg/kg body weight (corn oil) orally in the rat of group-IV, VI, VII and group-VIII. The clinical symptoms observed daily in each group and body weight were carried out at 15, 30 and 45 days of intervals. Clinical signs of reduced appetite, less water intake, decrease in body weight, organ weights, dry skin, rough hair coat, dullness, depression, emaciation and decrease in growth rate were observed after 15 days post feeding in the toxicity groups (II, III and V) but of milder intensity in the rat of ameliorative groups (IV, VI and VIII). The body weight gain revealed onset of significant reduction in the body weight from 15th day in the rat of toxicity groups (II, III and V) and ameliorative groups (IV, VI and VIII). [ABSTRACT FROM AUTHOR] |
