| Autor: |
Gustavsson, Carl Gunnar, Hansen, Ole, Frennby, Bo |
| Předmět: |
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| Zdroj: |
Scandinavian Cardiovascular Journal; May2004, Vol. 38 Issue 2, p75-79, 5p |
| Abstrakt: |
Objective --To evaluate troponin I > 99th percentile of normal as a criterion for myocardial injury after percutaneous coronary intervention (PCI). Design --Troponin I and creatine kinase monobasic (CK-MB) were measured in 327 patients before and after percutaneous transluminal coronary angioplasty (PTCA) with stent implantation. Results-Troponin I was elevated before PCI in 100 of a total of 222 patients with acute coronary syndrome (ACS). In 91 of these 100 patients, troponin I was elevated also after PCI but actual increases in troponin I concentrations from before to after PCI were found in only 32 patients. The increase of troponin I correlated with post-procedural CK-MB whereas post-procedural troponin I levels did not correlate. In the 122 patients with ACS but normal/normalized troponin I before PCI and in 105 patients with stable coronary artery disease post-procedural troponin I appeared to be a reliable indicator of myocardial infarction (MI), however more sensitive than CK-MB. Conclusion-Troponin I after PCI is sensitive to pre- procedural concentrations. To avoid false positive MI diagnoses we thus suggest that troponin I should be measured before as well as after the procedures and only actual increases should be regarded as indicating procedure-related MI. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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