| Autor: |
Pandey, Vishnudatt, Tiwari, Gargi, Mall, Vijaya Shri, Tiwari, Rakesh Kumar, Ojha, R. P., Shekhawat, Manoj Singh, Bhardwaj, Sudhir, Suthar, Bhuvneshwer |
| Předmět: |
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| Zdroj: |
AIP Conference Proceedings; 2018, Vol. 1953 Issue 1, pN.PAG-N.PAG, 4p |
| Abstrakt: |
HIV-1 envelope glycoprotein-mediated fusion is managed by the concerted coalescence of the HIV-1 gp41 N- and C- helical regions, which is a product in the formation of 6-helix bundles. These two regions are considered prime targets for peptides and antibodies that inhibit HIV-1 entry. There are so many rational method aimed to attach a rationally designed artificial tail to the C-terminus of HIV-1 fusion inhibitors to increase their antiviral potency. Here M. D. simulation was performed to go insight for study of C-terminal tail of Ile-Asp-Leu (IDL). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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