Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection.

Autor: Zanata, Silvio M., Lopes, Marilene H., Mercadante, Adriana F., Hajj, Glaucia N. M., Chiarini, Luciana B., Nomizo, Regina, Freitas, Adriana R. O., Cabral, L. B., Lee, Kil S., Juliano, Maria A., de Oliveira, Elizabeth, Jachieri, Saul G., Burlingame, Alma, Huang, Lan, Linden, Rafael, Brentani, Ricardo R., Martins, Vilma R.
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Zdroj: EMBO Journal; 7/1/2002, Vol. 21 Issue 13, p3307-3316, 10p
Abstrakt: Prions are composed of an isoform of a normal sialoglycoprotein called PrPc, whose physiological role has been under investigation, with focus on the screening for ligands. Our group described a membrane 66 kDa PrPc-binding prot [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index