The tripartite motif family identifies cell compartments.

Autor: Reymond, Alexandre, Meroni, Germana, Fantozzi, Anna, Merla, Giuseppe, Cairo, Stefano, Luzi, Lucilla, Riganelli, Daniela, Zanaria, Elena, Messali, Silvia, Cainarca, Silvia, Guffanti, Alessandro, Minucci, Saverio, Pelicci, Pier Giuseppe, Ballabio, Andrea
Předmět:
Zdroj: EMBO Journal; 5/1/2001, Vol. 20 Issue 9, p2140-2151, 12p
Abstrakt: A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index