Convenient and Inexpensive Route to Sulfonylated Pyridines via SNAr Reaction of Electron-Rich Pyridines by Iron Catalysis.

Autor:	Fei Chen, Chacón-Huete, Franklin, El-Husseini, Hassan, Forgione, Pat
Předmět:	PYRIDINE SULFONYL compounds IRON catalysts CHEMICAL yield DISPROPORTIONATION (Chemistry)
Zdroj:	Synthesis; 2018, Vol. 50 Issue 9, p1914-1920, 7p
Abstrakt:	Sulfonylated pyridines were synthesized in moderate to excellent yields, with a wide scope of substituted pyridines and sulfinate salts as starting materials, by an iron-catalyzed SNAr reaction. This new methodology exhibits advantages for the synthesis of these useful substrates, such as the use of a readily available, inexpensive catalyst, prevention of the disproportionation of the sulfinate salts, and, more importantly, providing access to electron-rich pyridine substr [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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