| Autor: |
CHEVAL, BORIS, BOISGONTIER, MATTHIEU P., ORSHOLITS, DAN, SIEBER, STEFAN, GUESSOUS, IDRIS, GABRIEL, RAINER, STRINGHINI, SILVIA, BLANE, DAVID, VAN DER LINDEN, BERNADETTE W. A., KLIEGEL, MATTHIAS, BURTON-JEANGROS, CLAUDINE, COURVOISIER, DELPHINE S., CULLATI, STEPHANE |
| Předmět: |
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| Zdroj: |
Age & Ageing; May2018, Vol. 47 Issue 3, p398-407, 10p, 2 Charts, 1 Graph |
| Abstrakt: |
Background: socioeconomic circumstances (SEC) during a person's lifespan influence a wide range of health outcomes. However, solid evidence of the association of early- and adult-life SEC with health trajectories in ageing is still lacking. This study assessed whether early-life SEC are associated with muscle strength in later life--a biomarker of health--and whether this relationship is caused by adult-life SEC and health behaviours. Methods: we used data from the Survey of Health Ageing and Retirement in Europe, a 12-year population-based cohort study with repeated measurement in six waves (2004-15) and retrospective collection of life-course data. Participants' grip strength was assessed by using a handheld dynamometer. Confounder-adjusted logistic mixed-effect models were used to examine the associations of early- and adult-life SEC with the risk of low muscle strength (LMS) in older age. Results: a total of 24,179 participants (96,375 observations) aged 50-96 living in 14 European countries were included in the analyses. Risk of LMS was increased with disadvantaged relative to advantaged early-life SEC. The association between risk of LMS and disadvantaged early-life SEC gradually decreased when adjusting for adult-life SEC for both sexes and with unhealthy behaviours for women. After adjusting for these factors, all associations between risk of LMS and early-life SEC remained significant for women. Conclusion: early-life SEC are associated with muscle strength after adjusting for adult-life SEC and behavioural lifestyle factors, especially in women, which suggests that early life may represent a sensitive period for future health. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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