Clinical Examination for Acute Aortic Dissection: A Systematic Review and Meta‐analysis.
Autor: | Ohle, Robert, Kareemi, Hashim Khaliq, Wells, George, Perry, Jeffrey J. |
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Předmět: |
AORTIC dissection
CONFIDENCE intervals MEDICAL databases INFORMATION storage & retrieval systems MEDICAL information storage & retrieval systems MEDLINE META-analysis ONLINE information services PHYSICAL diagnosis PROBABILITY theory STATISTICS SYSTEMATIC reviews SYMPTOMS CONTINUING education units DATA analysis software DESCRIPTIVE statistics ODDS ratio DIAGNOSIS DISEASE risk factors |
Zdroj: | Academic Emergency Medicine; Apr2018, Vol. 25 Issue 4, p397-412, 16p |
Abstrakt: | Abstract: Objectives: Acute aortic dissection is a life‐threatening condition due to a tear in the aortic wall. It is difficult to diagnose and if missed carries a significant mortality. Methods: We conducted a librarian‐assisted systematic review of PubMed, MEDLINE, Embase, and the Cochrane database from 1968 to July 2016. Titles and abstracts were reviewed and data were extracted by two independent reviewers (agreement measured by kappa). Studies were combined if low clinical and statistical heterogeneity (I2 < 30%). Study quality was assessed using the QUADAS‐2 tool. Bivariate random effects meta analyses using Revman 5 and SAS 9.3 were performed. Results: We identified 792 records: 60 were selected for full text review, nine studies with 2,400 participants were included (QUADAS‐2 low risk of bias, κ = 0.89 [for full‐text review]). Prevalence of aortic dissection ranged from 21.9% to 76.1% (mean ± SD = 39.1% ± 17.1%). The clinical findings increasing probability of aortic dissection were 1) neurologic deficit ( |
Databáze: | Complementary Index |
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