Autor: |
Rodriguez-Ruiz, Alejandro, Gubern-Merida, Albert, Imhof-Tas, Mechli, Lardenoije, Susanne, Wanders, Alexander J. T., Andersson, Ingvar, Zackrisson, Sophia, Lång, Kristina, Dustler, Magnus, Karssemeijer, Nico, Mann, Ritse M., Sechopoulos, Ioannis |
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Zdroj: |
European Radiology; May2018, Vol. 28 Issue 5, p1938-1948, 11p, 4 Color Photographs, 1 Diagram, 5 Charts, 3 Graphs |
Abstrakt: |
Purpose: To compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection.Materials and Methods: Six radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (medio-lateral oblique, MLO), 1v-DBT (MLO) + 1v-DM (cranio-caudal, CC) and two-view DM + DBT (2v-DM+2v-DBT). The second session involved only 2v-DM. Lesions were scored using BI-RADS® and level of suspiciousness (1-10). Sensitivity, specificity, receiver operating characteristic (ROC) and jack-knife alternative free-response ROC (JAFROC) were computed.Results: On average, 1v-DBT was non-inferior to any of the other protocols in terms of JAFROC figure-of-merit, area under ROC curve, sensitivity or specificity (p>0.391). While readers inexperienced with 1v-DBT screening improved their sensitivity when adding more images (69-79 %, p=0.019), experienced readers showed similar sensitivity (76 %) and specificity (70 %) between 1v-DBT and 2v-DM+2v-DBT (p=0.482). Subanalysis by lesion type and breast density showed no difference among modalities.Conclusion: Detection performance with 1v-DBT is not statistically inferior to 2v-DM or to 2v-DM+2v-DBT; its use as a stand-alone modality might be sufficient for readers experienced with this protocol.Key Points: • One-view breast tomosynthesis is not inferior to two-view digital mammography. • One-view DBT is not inferior to 2-view DM plus 2-view DBT. • Training may lead to 1v-DBT being sufficient for screening. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
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