One-view digital breast tomosynthesis as a stand-alone modality for breast cancer detection: do we need more?

Autor:	Rodriguez-Ruiz, Alejandro, Gubern-Merida, Albert, Imhof-Tas, Mechli, Lardenoije, Susanne, Wanders, Alexander J. T., Andersson, Ingvar, Zackrisson, Sophia, Lång, Kristina, Dustler, Magnus, Karssemeijer, Nico, Mann, Ritse M., Sechopoulos, Ioannis
Předmět:	TOMOSYNTHESIS BREAST cancer diagnosis DIGITAL mammography BREAST cancer MEDICAL screening BREAST tumor diagnosis BREAST MAMMOGRAMS COMPARATIVE studies RESEARCH methodology MEDICAL cooperation RESEARCH EVALUATION research RETROSPECTIVE studies RECEIVER operating characteristic curves
Zdroj:	European Radiology; May2018, Vol. 28 Issue 5, p1938-1948, 11p, 4 Color Photographs, 1 Diagram, 5 Charts, 3 Graphs
Abstrakt:	Purpose: To compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection.Materials and Methods: Six radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (medio-lateral oblique, MLO), 1v-DBT (MLO) + 1v-DM (cranio-caudal, CC) and two-view DM + DBT (2v-DM+2v-DBT). The second session involved only 2v-DM. Lesions were scored using BI-RADS® and level of suspiciousness (1-10). Sensitivity, specificity, receiver operating characteristic (ROC) and jack-knife alternative free-response ROC (JAFROC) were computed.Results: On average, 1v-DBT was non-inferior to any of the other protocols in terms of JAFROC figure-of-merit, area under ROC curve, sensitivity or specificity (p>0.391). While readers inexperienced with 1v-DBT screening improved their sensitivity when adding more images (69-79 %, p=0.019), experienced readers showed similar sensitivity (76 %) and specificity (70 %) between 1v-DBT and 2v-DM+2v-DBT (p=0.482). Subanalysis by lesion type and breast density showed no difference among modalities.Conclusion: Detection performance with 1v-DBT is not statistically inferior to 2v-DM or to 2v-DM+2v-DBT; its use as a stand-alone modality might be sufficient for readers experienced with this protocol.Key Points: • One-view breast tomosynthesis is not inferior to two-view digital mammography. • One-view DBT is not inferior to 2-view DM plus 2-view DBT. • Training may lead to 1v-DBT being sufficient for screening. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Full text from SpringerLink