| Autor: |
Frank, Karen M., Sekiguchi, JoAnn M., Seidl, Katherine J., Swat, Wojciech, Rathbun, Gary A., Hwei-Ling Cheng, Davidson, Laurie, Kangaloo, Landy, Alt, Frederick W. |
| Předmět: |
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| Zdroj: |
Nature; 11/12/1998, Vol. 396 Issue 6707, p173, 5p, 1 Color Photograph, 5 Black and White Photographs, 3 Diagrams, 2 Charts, 25 Graphs |
| Abstrakt: |
Presents research which showed the inactivation of the ligase IV gene in mice resulting in late embryonic lethality. Common factors in DNA-end-joining reactions and V(D)J recombination; Role of ligase IV; Blocked lymphopoiesis in such mice; Traits of ligase IV-deficient embryonic fibroblasts; Comparison of mice with those having Ku70 and Ku80 deficiencies; Viability of Ku-deficient mice. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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