Dust mite-induced asthma in cynomolgus monkeys.

Autor: Van Scott, Michael R., Hooker, Jerry L., Ehrmann, David, Shibata, Yoshimi, Kukoly, Cynthia, Salleng, Kenneth, Westergaard, Greg, Sandrasagra, Anthony, Nyce, Jonathan
Předmět:
Zdroj: Journal of Applied Physiology; Apr2004, Vol. 96 Issue 4, p1433-1444, 12p, 10 Diagrams, 3 Charts
Abstrakt: Reports on the development of nonhuman primate model of allergic asthma by sensitizing cynomolgius monkeys to dust mite antigen. Induction of asthmalike symptoms; Observation of smooth muscle hypertrophy in neonatally sensitized animals; Factor affecting the changes in airway resistance and dynamic compliance; Elevation of allergen-specific serum IgE and IgG levels.
Databáze: Complementary Index