| Autor: |
Hase, Jan C., Soder, Per-osten, Soder, Bkgitta, Kulstad, Soren, Kelty, Eva |
| Předmět: |
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| Zdroj: |
European Journal of Oral Sciences; Jun1995, Vol. 103 Issue 3, p172-178, 7p |
| Abstrakt: |
A double-blind, randomized, 2-wk experimental gingivitis clinical trial with cross-over design in 14 dental students was conducted in order to study the efficacy and safety of delmopinol hydrochloride solution (2 mg/ml), used with no other oral hygiene procedures, in comparison with placebo. Plaque formation was measured by the QUIGLEY & HEIN Plaque Index and gingivitis was assessed by bleeding on probing according to MÜHLEMANN & SON. Rinsing with delmopinol resulted in lower plaque scores compared to placebo. The development of gingivitis was weak during the 2-wk test periods, and thus no conclusive results were obtained. As in previous studies, the most frequent adverse event when rinsing with deimopinol was a transient anaesthetic sensation in the oral mucosa. The results showed that rinsing with delmopinol hydrochloride solution (2 mg/ml) for 60 s twice daily with no other oral hygiene procedures led to less plaque formation than rinsing with placebo. This study also showed good tolerance and acceptability of mouthrinsing with delmopinol. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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