| Abstrakt: |
Introduction: Thyroid swelling is common problem among South Asian women due to probable dietary, environmental and genetic factors. Although benign nodules far outnumber cancerous lesions, the risk of malignancy needs to be evaluated preoperatively to determine the extent of surgery1, 2.Thyroid nodules may cause hypothyroidism, hyperthyroidism, cosmetic issues, and problems in other organs such as compression, and they also have the potential for malignancy3. As FNAC for thyroid swelling was found to have superior diagnostic reliability over ultrasonography and thyroid scintigraphy, American thyroid association and national comprehensive cancer network endorsed it as an initial diagnostic test of choice 4. Hence, the accurateevaluation of thyroid nodules is very important. In recent years, the role of fine-needle aspiration cytology (FNAC)is increasing regarding the management methods as well as its role in detection of malignancy potentials ofthyroid nodules2. Method: All the cases of thyroid lesions received in the Department of Pathology, ESIC MC PGIMSR, Bangalore from January 2015 to December 2016 were reviewed and categorized using the Bethesda system. Histopathological correlation was done wherever possible. Results: A total of 963 cases were reviewed, mean age of the patients were 37.11(11-70). Among them 871 cases belonged to benign category, followed by 39 cases unsatisfactory, follicular neoplasm or suspicious of follicular neoplasm 20 cases, suspicious of malignancy 08 cases, malignant 17 cases and atypia of undetermined significance/follicular lesion of undetermined significance 08 cases. Histopathological correlation was available in 123 cases. Upon correlation, the sensitivity was 76.9 %, specificity 91.8%and accuracy was 92.6 %, with the positive predictive value of 62.5 %and negative predictive value of 97.19%. Conclusion: The results of this study showed high overall accuracy indicating that Bethesda system is a reliable and valid reporting system for thyroid cytology. Therefore it is recommended that Bethesda system can be used for initial workup of patients with thyroid lesions. [ABSTRACT FROM AUTHOR] |
