| Autor: |
KOUHEI TOKUYAMA, FUMITO OKADA, HARUKA SATO, SHUNRO MATSUMOTO, AKIRA MATSUMOTO, AYAKO HARUNO, KENJI KASHIMA, MASAO OGATA, EIICHI OHTSUKA, HIROMU MORI |
| Zdroj: |
British Journal of Radiology; Apr2017, Vol. 90 Issue 1072, p1-6, 6p, 4 Black and White Photographs, 2 Charts, 1 Graph |
| Abstrakt: |
Objective: This study aimed to compare CT findings in patients with Epstein–Barr virus positive (EBV+) diffuse large B-cell lymphoma (DLBCL) of the elderly with CT findings in patients with Epstein–Barr virus negative (EBV−) DLBCL. Methods: We retrospectively identified 9 consecutive patients with EBV+ DLBCL (6 males and 3 females; aged 72–83 years, mean: 76.2 years) and 39 consecutive patients with EBV− DLBCL (19 males and 20 females; aged 53–91 years, mean: 71.3 years) who had undergone CT examinations between September 2007 and August 2016. In each type of disease, clinical and CT findings were evaluated. Results: No significant differences in B symptom incidence or serum lactate dehydrogenase levels were found between the two diseases. However, the prognosis of patients with EBV+ DLBCL was significantly poorer than that of those with EBV− DLBCL (p < 0.05). Nodal and extranodal necrosis was found in 6 (66.7%) of 9 patients with EBV+ DLBCL and in 6 (15.4%) of 39 patients with EBV− DLBCL (p < 0.005). Conclusion: The CT finding of nodal and extranodal necrosis was significantly more frequent in patients with EBV+ DLBCL than in patients with EBV− DLBCL. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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