Effects of Low-Dose Dairy Protein Plus Micronutrient Supplementation during Resistance Exercise on Muscle Mass and Physical Performance in Older Adults: A Randomized, Controlled Trial.
| Autor: | Seino, Satoshi, Sumi, K., Narita, M., Yokoyama, Y., Ashida, K., Kitamura, A., Shinkai, S. |
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| Předmět: |
BIOPHYSICS
CONFIDENCE intervals DAIRY products DIAGNOSIS DIETARY supplements FOLIC acid GAIT in humans INGESTION MUSCLES PROTEINS STATISTICAL sampling SCIENTIFIC apparatus & instruments MICRONUTRIENTS VITAMIN B12 VITAMIN D RANDOMIZED controlled trials PRE-tests & post-tests INDEPENDENT living PHYSICAL activity FUNCTIONAL assessment DESCRIPTIVE statistics PHOTON absorptiometry RESISTANCE training |
| Zdroj: | Journal of Nutrition, Health & Aging; Jan2018, Vol. 22 Issue 1, p59-67, 9p |
| Abstrakt: | Objectives: To investigate whether supplementation with low-dose dairy protein plus micronutrients augments the effects of resistance exercise (RE) on muscle mass and physical performance compared with RE alone among older adults.Design: Randomized controlled trial.Setting: Tokyo, Japan.Participants: Eighty-two community-dwelling older adults (mean age, 73.5 years) were randomly allocated to an RE plus dairy protein and micronutrient supplementation group or an RE only group (n = 41 each).Intervention: The RE plus supplementation group participants ingested supplements with dairy protein (10.5 g/day) and micronutrients (8.0 mg zinc, 12 μg vitamin B12, 200 μg folic acid, 200 IU vitamin D, and others/day). Both groups performed the same twice-weekly RE program for 12 weeks.Measurements: Whole-body, appendicular, and leg lean soft-tissue mass (WBLM, ALM, and LLM, respectively) with dual-energy X-ray absorptiometry, physical performance, biochemical characteristics, nutritional intake, and physical activity were measured before and after the intervention. Data were analyzed by using linear mixed-effects models.Results: The groups exhibited similar significant improvements in maximum gait speed, Timed Up-and-Go, and 5-repetition and 30-s chair stand tests. As compared with RE only, RE plus supplementation significantly increased WBLM (0.63 kg, 95% confidence interval [CI]: 0.31-0.95), ALM (0.37 kg, 95% CI: 0.16-0.58), LLM (0.27 kg, 95% CI: 0.10-0.46), and serum concentrations of 25-hydroxyvitamin D (4.7 ng/mL, 95% CI: 1.6-7.9), vitamin B12 (72.4 pg/mL, 95% CI: 12.9-131.9), and folic acid (12.9 ng/mL, 95% CI: 10.3-15.5) (all P < 0.05 for group-by-time interactions). Changes over time in physical activity and nutritional intake excluding the supplemented nutrients were similar between groups.Conclusion: Low-dose dairy protein plus micronutrient supplementation during RE significantly increased muscle mass in older adults but did not further improve physical performance. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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