| Autor: |
Yang, Yang, Li, Shu‐jun, Pan, Jing‐Jing, Hu, Yu‐Hua, Zhou, Xiao‐Yu, Cheng, Rui, Chen, Xiao‐qing, Li, Shu-Jun, Pan, Jing-Jing, Hu, Yu-Hua, Zhou, Xiao-Yu, Chen, Xiao-Qing |
| Předmět: |
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| Zdroj: |
Journal of Paediatrics & Child Health; Mar2018, Vol. 54 Issue 3, p284-288, 5p, 1 Color Photograph, 3 Charts |
| Abstrakt: |
Aim: To determine the level of cystatin C (Cys-C) values in preterm babies for the purpose of becoming a good endogenous marker of renal function.Methods: A total of 366 very low-birthweight infants (including 70 extremely low-birthweight babies) with gestational age <37 weeks born in two centres were studied.Results: In very low-birthweight infants, the mean level of Cys-C was 1.96 ± 0.44 mg/L in blood samples taken on day 1, 1.78 ± 0.49 mg/L on day 7 and 1.71 ± 0.47 mg/L on day 28. In extremely low-birthweight infants, the mean level of Cys-C was 2.00 ± 0.49 mg/L on day 1, 1.63 ± 0.38 mg/L on day 7 and 1.62 ± 0.55 mg/L on day 28, respectively. Compared to serum creatinine and blood urea nitrogen, Cys-C level was independent of birthweight and gestational age.Conclusion: Cys-C is regarded as an alternative for assessing renal function in very low-birthweight infants, but its advantages over serum creatinine and blood urea nitrogen has not been fully proved yet. Hence, larger sample study is still necessary. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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