| Abstrakt: |
This paper presents data of 120 examined women diagnosed with chronic endometritis, 80 of them underwent needle-biopsy of the endometrium and 40 - hysteroscopy with diagnostic curettage of the uterine cavity. The diagnosis in all women is confirmed histologically. An analysis of endometrial microflora was performed in these women with an assessment of the morphofunctional state of the endometrium. It was found that in women with the viral component of chronic endometritis, the Epstein- Barr virus was the predominant infectious agents, HPV infection of high and medium oncogenic risk (with prevalence of types 16 and 18), and herpes simplex virus types 1 and 2, leading to chronic inflammatory process not independently, but most often in conjunction with the bacterial flora. Thus, viruses in the endometrium were found in 49% of women; in most cases, virus-bacterial associations were observed. It was also determined that certain differences in the chronic viral endometritis can be detected using immunohistochemistry and morphometric analysis. The data obtained make it possible to state that the immune component of the inflammatory reaction is more pronounced in the endometrium of the viral etiology, the viral infection enhances sclerotic processes and reduces the number of receptors for steroid hormones, especially for progesterone. [ABSTRACT FROM AUTHOR] |
