| Autor: |
Novakov, I., Brunilina, L., Vernigora, A., Kirillov, I., Mkrtchyan, A., Navrotskii, M., Sheikin, D., Yablokov, A., Ruchko, E., Kachala, V. |
| Předmět: |
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| Zdroj: |
Russian Journal of Organic Chemistry; Dec2017, Vol. 53 Issue 12, p1844-1850, 7p |
| Abstrakt: |
The aminolysis of 6-[1-(2,6-difluorophenyl)cyclopropyl]-5-methyl-2-(nitroamino)pyrimidin-4(3 H)-one with various amines in butan-1-ol and under solvent-free conditions is successful when the amino group in the reagent is sterically unshielded and the reaction medium is characterized by a high dielectric permittivity. Reactions of the title compound with sterically shielded amines are accompanied by alcoholysis where the amine acts as a base catalyst. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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