| Autor: |
Zheng, Na, Yao, Feihua, Liang, Xuefeng, Liu, Quan, Xu, Weifeng, Liang, Yan, Liu, Xiaobo, Li, Jun, Yang, Ruiyun |
| Zdroj: |
Natural Product Research; Apr2018, Vol. 32 Issue 7, p755-760, 6p |
| Abstrakt: |
A new phthalide derivative, xylarphthalide A (1), along with two known compounds (-)-5-carboxylmellein (2) and (-)-5-methylmellein (3), were isolated from the endophytic fungus Xylaria sp. GDG-102 cultured from the Chinese medicinal plant Sophora tonkinensis. Their structures were identified by MS and NMR experiments, and the absolute configuration of 1 was further confirmed by single-crystal X-ray diffraction analysis. Compound 1–3 showed antibacterial activities against Bacillus megaterium, Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Shigella dysenteriae with MIC values of 12.5–25 μg/mL. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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