HAEMATOBOCHEMICAL EVALUATION OF LEVOBUPIVACAINE WITH AND WITHOUT FENTANYL CITRATE IN COW CALVES.

Autor: Roonwal, G., Shukla, B. P., Shukla, S., Jain, R., Jaiswal, A.
Předmět:
Zdroj: Veterinary Practitioner; Jun2017, Vol. 18 Issue 1, p52-53, 2p
Abstrakt: The study was planned to evaluate the haemato-biochemical changes after epidural administration of levobupivacaine with and without fentanyl citrate. The study was conducted on 12 healthy cow calves, weighing between 50 to 70 kg. The animals were divided into two groups of six animals each. The animals of group I received levobupivacaine (@ 0. 8 mg/kg b. wt.) in sacrococcygeal space, while animals of group 2 received levobupivacaine (@ 0.8 mg/kg b.wt.) and Fentanyl citrate (@ 2 µg/kg b.wt.) simultaneously in the sacrococcygeal space. The clinico-physiological changes were recorded at different time intervals in both treatments. The animals of treatment 2 showed longer duration and good depth as compared to animals of treatment 1. The recovery was smooth in both groups. Haemato-biochemical parameters showed nonsignificant changes in their values in both the groups. Since the values of liver and kidney function tests did not show any significant changes, thus, it can be concluded that the drug is not hepato and nephro toxic and safe to be used in hepato-nephric compromised patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index