Phosphine catalysed (5 + 1) annulation of ynone/cinnamates with primary amines.

Autor: Ametovski, Jhi, Dutta, Uttam, Burchill, Laura, Maiti, Debabrata, Lupton, David W., Hooper, Joel F.
Předmět:
Zdroj: Chemical Communications; 12/18/2017, Vol. 53 Issue 97, p13071-13074, 4p
Abstrakt: The (5 + 1) annulation of ynone/cinnamates and related substrates with protected primary amines gives rise to isoquinolones, pyrrolidinones and pyrrolopiperazines in good to excellent yields under phosphine catalysis. The reaction is viable with chiral phosphines, although the selectivity is poor. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index