ALK-negative T-cell anaplastic large cell lymphoma associated with systemic lupus erythematosus.

Autor:	Suvajdzic, Nada, Stojanovic-Milenkovic, Roksanda, Tomasevic, Zoran, Cemerikic-Martinovic, Vesna, Mihaljevic, Biljana, Atkinson, Henry D E
Předmět:	CANCER chemotherapy CANCER SYSTEMIC lupus erythematosus TREATMENT effectiveness T-cell lymphoma DISEASE complications
Zdroj:	Medical Oncology; Dec2003, Vol. 20 Issue 4, p409-412, 4p
Abstrakt:	Patients with systemic lupus erythematosus (SLE) appear to have an increased risk of developing malignancies, especially lymphomas. We report the development of a systemic ALK-negative T-cell anaplastic large cell lymphoma, stage IIB, in a 53-yr-old Caucasian female with a 12-yr history of stable SLE. The patient responded poorly to chemotherapy and died 2 yr after diagnosis. Lymphomas that develop in patients with SLE and other autoimmune diseases are virtually always of B-cell origin. To our knowledge this is the first report of a T-cell anaplastic large cell lymphoma in a patient with SLE. This article discusses the association of SLE and lymphoma, with an emphasis on T-lymphoproliferative states. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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