| Autor: |
Xinchum Chen, Hamza A., Boping Zhou, Hamza A., Meizhong Li, Hamza A., Xiaorong Liang, Hamza A., Housheng Wang, Hamza A., Guilin Yang, Hui Wang, Xiaohua Le, Hamza A. |
| Předmět: |
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| Zdroj: |
Journal of Infectious Diseases; 4/1/2004, Vol. 189 Issue 7, p1158-1163, 6p |
| Abstrakt: |
Severe acute respiratory syndrome (SARS) is a novel infectious disease. No information is currently available on host-specific immunity against the SARS coronavirus (CoV), and detailed characteristics of the epidemiology of SARS CoV infection have not been identified. Of 36 patients with probable SARS CoV infection, 30 (83.3%) were positive for IgG antibody to SARS CoV; in contrast, only 3 of 48 patients with suspected SARS CoV infection, 0 of 112 patients with fever but without SARS, and 0 of 96 healthy control individuals were positive for it. IgG antibody to SARS CoV was first detected between day 5 and day 47 after onset of illness (mean ± SD, 18.7 ± 10.4). Detection of antibody to SARS CoV is useful in the diagnosis of SARS; however, at the incubation and initial phases of the illness, serological assay is of little value, because of late seroconversion in most patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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